GLP1 Clinics
Updated April 2026Sourced from FDA, NEJM

What GLP-1 medications actually cost in 2026.

Retail pricing, savings programs, insurance copays, and compounded alternatives compared in one place. Updated monthly with FDA-approved and 503A/503B pharmacy data.

Woman researching GLP-1 medication costs on laptop

$1,300

Retail

Brand, cash pay

$149

With savings

Mfr. coupon

$200

Compounded

503A/503B

Price Comparison at a Glance

Monthly cost by medication and payment type

semaglutide

Ozempic, Wegovy
Retail
$1,300/mo
With savings card
$499/mo−62%

semaglutide (oral)

Rybelsus, Wegovy Oral
Retail
$1,000/mo
With savings card
$149/mo−85%

tirzepatide

Mounjaro, Zepbound
Retail
$1,100/mo
With savings card
$299/mo−73%

orforglipron

Foundayo
Retail
$649/mo
With savings card
$149/mo−77%

Compounded options

Not FDA-approved

Prepared by 503A/503B pharmacies. Discuss risks with your provider.

semaglutide
$200/mo
tirzepatide
$250/mo

Detailed Pricing

Retail Prices (without insurance)

semaglutide

Ozempic, Wegovy

$1,300/mo

semaglutide (oral)

Rybelsus, Wegovy Oral

$1,000/mo

tirzepatide

Mounjaro, Zepbound

$1,100/mo

orforglipron

Foundayo

$649/mo

Savings Programs & Copay Cards

semaglutide

Novo Nordisk

$499/mo

Save 62%

semaglutide (oral)

Novo Nordisk

$149/mo

Save 85%

tirzepatide

Eli Lilly

$299/mo

Save 73%

orforglipron

Eli Lilly

$149/mo

Save 77%

Compounded Options (Not FDA-Approved)

compounded semaglutide

Various 503A/503B pharmacies

$200/mo

compounded tirzepatide

Various 503A/503B pharmacies

$250/mo

retatrutide

Eli Lilly

N/A/mo

Insurance Coverage

Usually covered

  • Type 2 diabetes diagnosis
  • BMI 30+ with prior authorization
  • Employer plans with weight management benefits

Often not covered

  • Weight loss only (no diabetes diagnosis)
  • Medicare Part D for weight loss
  • Compounded medications
  • Without prior authorization

Contact your insurance provider directly to confirm your specific coverage and out-of-pocket costs.

Total Program Costs

Beyond medication, here's what a complete GLP-1 program typically costs:

Initial Consultation

First visit including labs and evaluation

$100 – $300

Monthly Medication

Depends on brand vs. compounded

$149 – $1,300

Follow-Up Visits

Monthly or quarterly check-ins

$50 – $150

Lab Work

Periodic blood work monitoring

$50 – $200

Insurance Coverage Guides

Detailed breakdowns of GLP-1 coverage by insurer, plus savings programs to lower your costs. See our full insurance coverage guide for Medicare Part D timelines and state-by-state Medicaid coverage.

Aetna GLP-1 Coverage

Wegovy and Zepbound coverage details

Blue Cross Blue Shield

BCBS plan coverage and prior auth

UnitedHealthcare Coverage

UHC commercial and Medicare Advantage

Cigna GLP-1 Coverage

Cigna weight loss medication benefits

Medicare Coverage 2026

Part D rules and pending legislation

Medicaid by State

State-by-state Medicaid coverage

Wegovy Savings Guide

Pill and pen coupons compared side by side

Wegovy Cost Breakdown

Pill vs pen pricing dose by dose

Zepbound Cost Breakdown

List price, insured rate, and cash pay compared

Zepbound Savings Guide

Every active coupon and savings program

GLP-1 Cost Questions, Answered

18 of the most-searched cost questions, with sourced answers.

By medication
How much does Zepbound cost without insurance?
Zepbound (tirzepatide) retails for approximately $1,060-1,200/month without insurance. Eli Lilly offers a savings card that brings the out-of-pocket cost to around $499/month for uninsured patients. With commercial insurance, the copay can be as low as $25/month. Costco pharmacies often have lower retail prices than chain pharmacies. The cost is the same regardless of your dose since all Zepbound pens are priced equally.
What does Zepbound cost with insurance?
With commercial insurance that covers weight loss medications, Zepbound copays typically range from $25-150/month after prior authorization. Many employer-sponsored plans now include obesity treatment as a covered benefit. If your plan does not cover Zepbound specifically, ask your provider about Mounjaro (same active ingredient, tirzepatide) which may be covered under a diabetes indication. See our insurance coverage guide for insurer-specific details.
How much does Mounjaro cost per month?
Mounjaro costs approximately $1,000-1,200/month at retail price. With Eli Lilly's savings card, eligible patients pay as little as $25/month with commercial insurance or around $499/month without. Mounjaro is more commonly covered by insurance than Zepbound since it has a type 2 diabetes indication. Monthly cost stays the same across dose levels from 2.5mg through 15mg.
How much does Mounjaro cost without insurance?
Without insurance, Mounjaro's retail price is approximately $1,000-1,200/month. Costco and other warehouse pharmacies may offer slightly lower pricing. Lilly's savings card can reduce the cost to approximately $499/month for cash-pay patients. Compounded tirzepatide (the active ingredient in Mounjaro) is available from specialty pharmacies for $200-400/month as a lower-cost alternative.
How much does Wegovy cost without insurance?
Wegovy (semaglutide 2.4mg) costs approximately $1,300-1,350/month at retail, making it the most expensive brand-name GLP-1 for weight loss. Novo Nordisk offers a savings card for eligible patients. The new oral Wegovy pill has similar pricing to the injectable version. Compounded semaglutide offers the same active ingredient starting around $149-300/month through telehealth providers.
What is Wegovy's out-of-pocket cost?
Wegovy's out-of-pocket cost depends on your coverage. At full retail: approximately $1,300/month. With commercial insurance: typically $25-150/month after prior authorization. Without insurance but using the Novo Nordisk savings card: varies by eligibility. CVS, Walmart, and other major pharmacies carry Wegovy, but pricing can differ. Check our Wegovy savings guide for current discount programs.
How much does the Wegovy pill cost?
The oral Wegovy pill (oral semaglutide for weight loss) costs approximately $1,300/month at retail, similar to the injectable version. Without insurance, the out-of-pocket cost remains high. The GLP-1 pill form eliminates the need for injections but does not offer a price advantage over the shot. Novo Nordisk's savings program may apply to the oral formulation as well. Read our Wegovy pill vs. injection guide for a full comparison.
How much does tirzepatide cost?
Brand-name tirzepatide (sold as Mounjaro for diabetes or Zepbound for weight loss) costs $1,000-1,200/month at retail. Compounded tirzepatide from 503A/503B pharmacies costs $200-400/month. There is no generic tirzepatide available yet. Insurance coverage depends on the indication and your specific plan. The cost is the same across all dosage levels.
How much does semaglutide cost per month?
Monthly semaglutide costs vary widely by formulation. Brand-name injectable Wegovy: $1,300/month retail. Brand-name Ozempic (diabetes indication): $900-1,100/month. Oral semaglutide (Rybelsus 14mg): $900-1,000/month. Compounded semaglutide: $149-300/month. With insurance and savings programs, brand-name costs can drop to $25-150/month.
Compounded options
How much does compounded semaglutide cost?
Compounded semaglutide typically costs $149-300/month depending on the provider and dosage. Online telehealth companies offer compounded semaglutide programs that include the medication, provider consultations, and ongoing monitoring. Compounded versions are not FDA-approved but contain the same active ingredient. Compare providers on our telehealth comparison page to find the best price.
How much does compounded tirzepatide cost?
Compounded tirzepatide ranges from $200-400/month through specialty compounding pharmacies. This is significantly less than brand-name Mounjaro or Zepbound ($1,000-1,200/month). Pricing varies by dosage and provider. Like all compounded medications, these are not FDA-approved. Use our provider quiz to find telehealth companies offering compounded tirzepatide.
Insurance & Medicare
How much do GLP-1 medications cost without insurance?
Without insurance, GLP-1 medications range from $149/month (compounded) to $1,350/month (brand-name Wegovy). Zepbound and Mounjaro retail for $1,000-1,200/month, while Ozempic is $900-1,100/month. Manufacturer savings cards can reduce costs by 50% or more. Compounded versions offer the most affordable path at $149-400/month. See our savings guide for all available discount programs.
How much do GLP-1 medications cost with insurance?
With commercial insurance that covers weight loss treatment, GLP-1 copays are typically $25-150/month. Coverage usually requires prior authorization and may require documented BMI of 30+ (or 27+ with comorbidities). Medicare Part D does not currently cover weight loss GLP-1s but legislation pending for July 2026 may change this. Medicaid coverage varies by state. Check our insurer-specific guides above for details on Aetna, BCBS, UnitedHealthcare, and Cigna.
Does Medicare cover Ozempic or Wegovy?
Medicare Part D covers Ozempic when prescribed for type 2 diabetes but does not currently cover it for weight loss alone. Wegovy and Zepbound are not covered by Medicare for weight loss. The Treat and Reduce Obesity Act, if passed, would extend Medicare coverage to anti-obesity medications starting July 2026. Medicare Advantage plans may offer supplemental weight management benefits. See our Medicare GLP-1 coverage guide for the latest updates.
Comparisons & telehealth
Zepbound vs. Wegovy: which costs less?
Zepbound ($1,060-1,200/month) is slightly less expensive than Wegovy ($1,300-1,350/month) at retail. Both have manufacturer savings cards, but Zepbound's savings program currently offers a better cash-pay discount (~$499/month vs. varying discounts for Wegovy). Insurance coverage may differ since they contain different active ingredients (tirzepatide vs. semaglutide). Compare them in detail on our Wegovy vs. Zepbound comparison.
Tirzepatide vs. semaglutide: which is cheaper?
At retail, tirzepatide-based medications (Mounjaro/Zepbound at $1,000-1,200/month) are slightly less expensive than semaglutide-based Wegovy ($1,300/month). For compounded versions, both are in the $149-400/month range. The real cost difference often comes down to insurance coverage and which savings programs you qualify for. Tirzepatide may have an edge because Mounjaro's diabetes indication gives it broader insurance coverage.
What is the cheapest GLP-1 medication available?
Compounded semaglutide is the most affordable GLP-1 option, starting around $149/month from online telehealth providers. Compounded tirzepatide starts around $200/month. Among brand-name medications, using manufacturer savings cards with commercial insurance can bring costs as low as $25/month. Without insurance, Lilly's savings card for Zepbound/Mounjaro ($499/month) is typically the cheapest brand-name path. Take our provider quiz to find the most affordable option for your situation.
How much do Hims, Ro, and other telehealth GLP-1 programs cost?
Telehealth GLP-1 programs vary significantly in price. Programs using compounded medications typically range from $149-349/month and include the medication, provider visits, and monitoring. Programs prescribing brand-name medications charge a consultation fee ($50-300) plus the pharmacy cost of the drug. Some comprehensive programs (with coaching, nutrition, and ongoing support) run $400+/month. Compare all providers side-by-side on our telehealth comparison page.

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