★ 5.0(5 reviews)
ListedTelehealthIn-Person
We evaluated Sioux Falls's GLP-1 providers and ranked the top 10 based on patient ratings, verified reviews, provider credentials, pricing transparency, and telehealth availability. These clinics average a 5.0-star rating and represent the best options for GLP-1 treatment in Sioux Falls, South Dakota.
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Our rankings are based on a weighted scoring system that considers multiple factors. Patient ratings carry the most weight, followed by the number of verified reviews, provider credentials (including ABOM board certification in obesity medicine), and verification level. We also factor in pricing transparency, whether the clinic is accepting new patients, and telehealth availability. Clinics that provide clear pricing information, accept insurance, and offer flexible visit options score higher because these factors directly affect your ability to access and afford treatment. Every clinic listed has been verified through NPI Registry data.
10 weight loss clinics prescribing GLP-1 medications in Sioux Falls accept health insurance. Commonly accepted plans include Medicaid, Medicare.
Yes. 6 weight loss doctors serving Sioux Falls offer virtual GLP-1 consultations, allowing you to get a semaglutide or tirzepatide prescription and have medication shipped to your door without an in-person visit. Compare top telehealth GLP-1 providers.
Obesity medicine providers in Sioux Falls prescribe semaglutide, tirzepatide. Your weight loss doctor will recommend the best GLP-1 injection based on your health history, BMI, and treatment goals. Compare all GLP-1 weight loss medications.
Sioux Falls has something most mid-size cities lack: two competing major health systems headquartered in the same town. Sanford Health and Avera Health both run comprehensive weight management programs with board-certified obesity medicine specialists, and that competition benefits patients through better access and more options. Beyond the big systems, independent clinics and telehealth providers have entered the market, giving this city of 210,000 a surprisingly deep roster of GLP-1 options.
The city layout is straightforward. I-29 runs north-south, I-90 runs east-west, and most clinics cluster along Minnesota Avenue, Louise Avenue on the south side, or near the medical campuses on either side of town. The east side, home to a growing refugee and immigrant population from Ethiopia, Sudan, and Myanmar, is underserved by specialty care compared to the newer developments on the south and west sides. Telehealth fills that gap, especially for patients who work shifts at Smithfield or the other processing plants.
Food culture here is unapologetically Midwestern. Chislic, deep-fried cubes of lamb or beef sprinkled with garlic salt, is the unofficial state snack and shows up at every bar and VFW in town. German-Russian heritage means lots of kuchen, knoephla soup, and fleischkuechle at places like Skelly's Pub. The growing refugee communities have added Ethiopian injera spots and Karen cuisine to the mix. A GLP-1 provider who hands out a generic meal plan without understanding these food traditions is going to lose patients fast.
The practical reality of GLP-1 treatment in Sioux Falls comes down to insurance and weather. South Dakota has no state income tax, which attracts retirees and high earners, but Medicaid coverage for GLP-1s remains limited. The brutal winters, with wind chills hitting minus 30, mean outdoor activity drops to near zero from December through March. Providers who build seasonal adjustments into their care plans and offer indoor activity guidance during those months deliver better outcomes than those running the same protocol year-round.
Monthly GLP-1 programs in Sioux Falls typically run $225 to $400 for compounded semaglutide and $600 to $1,000 for brand-name Wegovy or Zepbound. Both Sanford and Avera offer structured weight management programs, though pricing varies based on insurance coverage and program tier.
Many commercial plans in South Dakota cover GLP-1 medications with prior authorization. Employer plans through Sanford, Avera, and major employers like Citibank and Wells Fargo tend to have decent formulary coverage. South Dakota Medicaid coverage for weight loss medications has been more restrictive than many neighboring states.
Most clinics are near the two major medical campuses: Sanford on the north side near Falls Park and Avera on the southeast side near Louise Avenue. Additional options exist along Minnesota Avenue and the south side retail corridors. The east side has fewer options, making telehealth important for that part of town.
We email when local providers open, change pricing, or start accepting new patients.
This site is for educational purposes only and is not medical advice. Always consult a healthcare provider before starting any medication. Full disclaimer
10 GLP-1 clinics in Sioux Falls are currently accepting new patients. Availability can change, so we recommend contacting the clinic directly to confirm openings and schedule your first consultation.
Yes. South Dakota allows telehealth prescribing for GLP-1 medications. Telehealth is especially useful for patients on the east side or those working shifts at the processing plants who struggle with traditional office hours.
The brutal winters from December through March limit outdoor activity significantly. Good providers here build seasonal adjustments into treatment plans, recommend indoor alternatives at places like the Midco Aquatic Center, and adjust expectations during the coldest months when activity naturally drops.
Look for board certification in obesity medicine or endocrinology. Sanford and Avera both set high standards with their structured programs. Any provider should include metabolic bloodwork, structured follow-up, and nutritional guidance that goes beyond generic templates.
10 GLP-1 clinics in Sioux Falls accept insurance. Commonly accepted plans include Medicaid, Medicare. Coverage varies by plan and medication. Contact the clinic directly to verify your specific plan is accepted before your visit.
Yes. 6 providers serving Sioux Falls offer telehealth GLP-1 consultations. South Dakota permits telehealth prescribing for weight loss medications. You can complete your consultation via video call and have medication shipped directly to your home.
Yes. 10 GLP-1 clinics in Sioux Falls are currently accepting new patients. Availability can change, so we recommend scheduling your consultation promptly to secure a spot.
Clinics in Sioux Falls prescribe semaglutide, tirzepatide. Your provider will determine the best medication based on your health history, weight loss goals, and insurance coverage.
Use our directory to browse 19 verified weight loss doctors and obesity medicine specialists in Sioux Falls, South Dakota. Filter by medication (semaglutide, tirzepatide), insurance accepted, and telehealth availability to find the right provider for your needs.
Most medical weight loss clinics in Sioux Falls do not require a referral. You can schedule a consultation directly with an obesity specialist or weight management provider. Some insurance plans may require a referral from your primary care physician for coverage purposes.
GLP-1 Medications
Compare Ozempic, Wegovy, Mounjaro, and more
