Reviewed by RC Nelson, Health & Wellness Writer. Last updated April 2026.
Key Takeaways
- Semaglutide from $175 first month ($275/mo ongoing, or $206/mo on 6-month plan)
- Tirzepatide from $285 first month ($385/mo ongoing, or $325/mo on 6-month plan)
- Onboarding call with your provider included with all plans
- Free UPS 2-Day Air shipping
- Financing through Klarna, Affirm, and Afterpay
- 4.6/5 Trustpilot rating from 900+ reviews
- Available in all 50 states
- Yucca Health Review 2026: - Semaglutide from $175 first month ($275/mo ongoing, or $206/mo on 6-month plan)
- $99/mo bargain here, but you are getting a more hands-on experience than what most budget platforms offer.
- That matters, especially if you have questions about dosing, side effects, or what to expect.
- Always consult a qualified healthcare provider before starting, stopping, or changing any medication.
What Is Yucca Health?
Yucca Health is a telehealth platform that prescribes compounded semaglutide and tirzepatide for weight loss. What sets them apart from the pack is a few things: flexible plan lengths that actually save you money, an onboarding call with your provider (not just a chatbot), and a Trustpilot score that suggests they are doing something right.
The pricing is mid-range. You are not getting GobyMeds' $99/mo bargain here, but you are getting a more hands-on experience than what most budget platforms offer.
Pricing Breakdown
Yucca Health runs three pricing tiers depending on how long you commit:
Semaglutide+
| Plan | First Month | Ongoing |
|---|---|---|
| Monthly | $175 | $275/mo |
| 3-month | $165 | $255/mo |
| 6-month | $146 | $206/mo |
Tirzepatide+
| Plan | First Month | Ongoing |
|---|---|---|
| Monthly | $285 | $385/mo |
| 3-month | $265 | $355/mo |
| 6-month | $258 | $325/mo |
The 6-month plan is where the real value is. You are saving nearly $70/mo on semaglutide compared to month-to-month. And with Klarna, Affirm, and Afterpay available on the 6-month plans, you can spread those payments out.
For context, here is how Yucca stacks up:
| Provider | Semaglutide Monthly |
|---|---|
| GobyMeds | From $99/mo |
| Henry Meds | $149-349/mo |
| Hims | $199-349/mo |
| Yucca Health | $206-275/mo |
| Ro | $149-499/mo |
Not the cheapest, but not the most expensive either. You are paying for the extras.
How It Works
- Complete a medical intake. Standard health history questionnaire covering your weight, medications, conditions, and goals.
- Identity verification. Quick ID check before your information goes to a provider.
- Provider review. A licensed US provider reviews your information within 24 hours. This part is async.
- Onboarding call. Here is where Yucca differs. You get a scheduled call with your provider to walk through your treatment plan, discuss dosing, set expectations, and answer questions. This is not a chatbot. It is a real conversation with the person managing your care.
- Medication ships. Your medication (with a B12 vitamin boost) arrives via UPS 2-Day Air with an injection kit included.
Medications
Compounded Semaglutide+ includes the active GLP-1 ingredient plus a B12 vitamin boost. Same core compound as Ozempic and Wegovy, prepared by a compounding pharmacy.
Compounded Tirzepatide+ is the dual-action GLP-1/GIP option, also with a B12 boost. Same active ingredient as Mounjaro and Zepbound.
Both formulations include additives selected for your needs. This is standard for compounding pharmacies and some patients actually prefer the added vitamins.
No brand-name options available. If you need FDA-approved Wegovy or Zepbound, look at Eden, Ro, or PlushCare.
Pros
The onboarding call is a real differentiator. Most telehealth GLP-1 platforms are fully async. You fill out a form, a provider glances at it, and your medication shows up. Yucca gives you an actual conversation with your provider before you start treatment. That matters, especially if you have questions about dosing, side effects, or what to expect.
Flexible plans save real money. The jump from $275/mo to $206/mo on the 6-month semaglutide plan is significant. Over six months, that is over $400 in savings. And the financing options make the upfront commitment more manageable.
Trustpilot speaks for itself. 4.6 out of 5 from 900+ reviews is strong. That is not a curated testimonial page on their own website. That is real patients leaving real feedback on a third-party platform.
2-Day shipping is standard. Not a premium upgrade. Every order ships UPS 2-Day Air at no extra cost.
Cons
$275/mo ongoing is not cheap. If you are on the monthly plan, you are paying more than Hims, Henry Meds, or GobyMeds for compounded semaglutide. The value equation only tips in Yucca's favor if you commit to a longer plan.
No brand-name options. Compounded only. If you want or need FDA-approved medications, Yucca cannot help.
Auto-renewal. Plans auto-renew, which means you need to actively cancel if you want to stop. Not unusual in this space, but worth knowing.
Yucca Health vs. the Competition
| Feature | Yucca Health | Henry Meds | Hims | GobyMeds |
|---|---|---|---|---|
| Semaglutide from | $206-275/mo | $149/mo | $199/mo | $99/mo |
| Tirzepatide | Yes ($325-385/mo) | Yes ($149-349/mo) | No | Yes ($133/mo) |
| Provider call | Yes (onboarding) | No | No | No |
| Financing | Klarna/Affirm/Afterpay | No | No | No |
| Shipping | Free 2-Day Air | Free | Free | Free |
| Trustpilot | 4.6/5 (900+ reviews) | N/A | N/A | N/A |
| Insurance | No | No | No | No |
Who Is Yucca Health Best For?
Yucca Health makes the most sense for patients who want more than a medication-in-a-box experience. If talking to your provider before starting treatment matters to you, if you prefer a platform with strong third-party reviews, and if you can commit to a longer plan to unlock the better pricing, Yucca delivers.
It is not the right choice if you are strictly optimizing for the lowest price. GobyMeds at $99/mo or Henry Meds at $149/mo will save you significant money for similar compounded medications.
The right GLP-1 medication depends on your individual health profile, not just price or average weight loss numbers. Talk to your provider about your medical history, current medications, and treatment goals before making a decision.
The Bottom Line
Yucca Health sits in the middle of the GLP-1 telehealth market on price, but above average on patient experience. The onboarding provider call, flexible plan lengths, 2-day shipping, and financing options add up to a more thoughtful experience than most budget competitors offer. The 4.6 Trustpilot rating from 900+ reviews backs that up.
The key is committing to the 6-month plan. At $206/mo for semaglutide, the pricing becomes competitive and the extras start to feel like genuine value rather than a markup. On the monthly plan at $275/mo, you are paying a premium that is harder to justify.
Want to learn more? See Yucca Health's current plans and pricing to find the right fit.
Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Individual results vary. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you are experiencing a medical emergency, call 911.