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GLP-1 News & Updates

FDA updates, drug pricing news, insurance coverage changes, and the latest clinical trial results for GLP-1 weight loss medications.

The Dose

European Panel Backs Wegovy HD: Single-Dose 7.2mg Pen Moves Closer to EU Approval

EMA's CHMP recommends approval of Wegovy 7.2mg in convenient single-dose pen format, bringing 20.7% weight loss results to European patients by Q3 2026.

The Dose

TrumpRx Launches with Historic $350 GLP-1 Pricing, Transforming Access

Government platform TrumpRx launched in February with GLP-1 drugs at $150-350/month, slashing costs 75% and expanding Medicare coverage for obesity for the first time.

The Dose

FDA Issues 30 Warning Letters to Telehealth Firms for Misleading GLP-1 Claims

FDA escalates enforcement against telehealth companies marketing compounded GLP-1 drugs as identical to approved medications like Wegovy and Zepbound.

The Dose

Scientists Find Way to Extend GLP-1 Weight Loss, Break Drug Plateaus

NIH study reveals cellular mechanism behind GLP-1 weight loss plateaus and shows existing drug roflumilast could extend semaglutide effects, reducing injection frequency.

The Dose

Bariatric Surgery Plunges 34% as GLP-1 Drugs Surge 140% in Historic Shift

New JAMA Surgery study reveals dramatic shift in obesity treatment as GLP-1 prescriptions more than double while bariatric surgeries fall to lowest levels since 2020.

The Dose

FDA Demands Post-Approval Safety Studies for New GLP-1 Pill Foundayo

FDA requests extensive safety studies for Eli Lilly's newly approved Foundayo (orforglipron) due to limited long-term data on the first small-molecule GLP-1 weight loss pill.

The Dose

FDA Approves Wegovy HD: Highest-Dose GLP-1 Delivers Record 21% Weight Loss

FDA approved 7.2mg semaglutide injection in record 54 days, delivering 20.7% average weight loss - the most effective obesity treatment ever approved.

The Dose

GLP-1 Drugs May Prevent Cancer from Spreading, Major Study Finds

Cleveland Clinic study of 10,000+ cancer patients shows GLP-1 drugs like Wegovy and Zepbound reduced risk of metastatic progression by up to 45%, especially in breast cancer.

The Dose

Wegovy Pill Now Available: First GLP-1 Oral Weight Loss Drug Hits US Market

Novo Nordisk officially launches Wegovy pill with $149 cash pricing, becoming the first oral GLP-1 drug for weight loss available in US pharmacies nationwide.

The Dose

Retatrutide Shows Record 28% Weight Loss in Breakthrough Phase 3 Trial

Eli Lilly's experimental triple-agonist retatrutide delivered up to 70 pounds weight loss in Phase 3 trial, matching bariatric surgery outcomes and setting new benchmark for obesity medications.

The Dose

CMS BALANCE Model Launches This Month: Medicaid GLP-1 Coverage Expands

CMS's voluntary BALANCE Model begins expanding Medicaid GLP-1 coverage this month, with Medicare Bridge program following in July at $50/month.

The Dose

Oral GLP-1 Drugs Target Brain's Reward Center for First Time, NIH Study Finds

NIH-funded study reveals small-molecule GLP-1 drugs like orforglipron penetrate deeper into the brain to suppress pleasure-based eating by targeting the central amygdala.

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